Sun J, Bi L, Chi Y, Huang G, Fan C, Aoki K, Kono A, Hui T, Misumi J.
The Impact of Ovarian Cancer on Life Expectancy in Japan.
Journal of Applied Statistics 2007;34:741-747.
Juan Sun, Kazuo Aoki, Jin-Xu Zheng, Bing-Zhong Su,
Xiao-Hui Ouyang, Junichi Misumi.
Effect of Nacl and Helicobacter pylori vacuolating cytotoxin
on cytokine expression and viability.
World J Gastroenterol 2006;12:2174-2180.
Juan Sun, Kazuo Aoki, Wei Wang, Aimin Guo, Junichi Misumi.
Sodium nitrite-induced cytotoxicity in cultured human gastric epithelial cells.
Toxicol In Vitro 2006;20:1133-1138.
Aoki K, Misumi J, Wang J, Jiang H, Sun J.
Cervical cancer trends related to mortality in Japan.
J Turkish-German Gynecol Assoc 2006;7:292-296.
Aoki K, Sun J, Kono A, Misumi J.
Suicide and homicide effects on life expectancy and mortality in Ireland.
Homeostasis 2005;43:128-135.
Esaki F, Sugita S, Akashi H, Kudo M, Aoki K.
Perception of the normalization principle by the providers
and recipients of home care and determinant factors.
J Phys Fit Nutr Immunol 2005;15:9-21.
Paul E. Kihaile, Kazuo Aoki, Noriyuki Kimura, Wei Pei, Junichi Misumi.
Are sperm parameters the best indicator of 2, 5-hexanedione reproductive toxicity
in male rats? Reproductive Toxicology 2005;20:515-519.
Kazuo Aoki, Paul E. Kihaile, Zhao Wenyuan, Zhang Xianghang,
Mercedes Castro, Mildre Disla, Thomas Nyambo, Junichi Misumi.
Comparison of prevalence of chronic atrophic gastritis
in Japan, China, Tanzania, and the Dominican Republic.
Ann Epidemiol 2005;15:598-606.
Kazuo Aoki, Juan Sun, Akihiro Kono, Junichi Misumi.
Age-related characteristics of uterine cancer mortality in Japan.
Arch Gynecol Obstet 2005;273:110-114.
Juan Sun, Lifu Bi, Yaojun Chi, Kazuo Aoki, Junichi Misumi.
Effect of sodium acetate on cell proliferation and induction
of proinflammatory cytokines: a preliminary evaluation.
Food Chem Toxicol 2005;43:1773-1780.
Aoki K, Misumi J, Miyakita T.
Questionnaire study on “green tobacco sickness” (GTS) in tobacco harvesters
in the South of Japan.
J Phys Fit Nutr Immunol 2004;14:12-24.
Kazuo Aoki, Junichi Misumi, Wenyuan Zhao, Xianghon Zhang, Zhengguo Zhang.
A field survey on some gastric cancer-associated carcinogenic factors
in areas of high and low gastric cancer mortality in China.
Journal of Physical Fitness Nutrition and Immunology 2004;14:3-11.
Paul E.Kihaile, Ramzy E. Kisanga, Kazuo Aoki,
Yoko Kumasako, Junichi Misumi, Takafumi Utsunomiya.
Embryo outcome in Y-Chromosome Microdeleted Infertile Males after ICSI.
Molecular reproduction and development 2004;68:176-181.
Kazuo Aoki, Paul E Kihaile, Junichi Misumi, Wei Pei, Masanobu Kudo.
Reproductive toxicity of 2,5-hexanedione in male rats.
Reproductive Medicine and Biology 2004;3:59-62.
Kazuo Aoki, Paul E Kihaile, Mercedes Castro, Mildre Disla,
Thomas B. Nyambo, Junichi Misumi.
Seroprevalences of Helicobacter pylori infection and chronic
atrophic gastritis in the united republic of Tanzania
and the Dominican Republic.
Environmental Health and Preventive Medicine 2004;9:170-175.
Ono S, Kudo M, Aoki K, Ezaki F, Misumi J.
Effect of mass immunization against influenza encephalopathy
on mortality rates in children.
Pediatr Int 2003;45:680-687.
F.Ma, J.Misumi, W.Zhao, K.Aoki, M. Kudo.
Long-term treatment with sterigmatocystin, a fungus toxin,
enhances the development of intestinal metaplasia of gastric mucosa
in Helicobacter pylori-infected Mongolian gerbils.
Scand J Gastroenterol 2003;38:360-369.
Zhang X, Zhao W, Sun X, Bo Y, Yan X, Wang J, Wang H, Zhang Z, Mi J,
Xie T, Misumi J, Aoki K, Wang F.
Radioimmunological analysis on serum pepsinogen
and gastrin of rural adult residents in high risk area of gastric cancer.
China Public Health 2002;18:287-288.
Zhang X, Wang JL, Yan X, Zhang Z, Mi J, Bo Y, Zhao W, Wang F, Misumi J, Aoki K.
Brief introduction of studies on screen methods for gastric cancer
in Zhanhuang Country.
Chinese J Tumor 2002;11:384-385.
J Sun, J Misumi, A Shimaoka, K Aoki, A Kono.
Stomach cancer-related mortality rate is higher
in young Japanese women than in men.
Public Health 2002;116:39-44.
Ma F, Zhao W, Kudo M, Aoki K, Misumi J.
Inhibition of vacuolation toxin activity of Helicobacter pylori by iodine,
nitrite and potentiation by sodium chloride, sterigmatocystin and fluoride.
Toxicol In Vitro 2002;16:531-537.
J Sun, J Misumi, A Shimaoka, K Aoki, F Esaki.
Stomach cancer-related mortality.
Eur J Cancer Prev 2001;10:61-67.
Kumamoto T, Sannomiya K, Ueyama H, Aoki K, Nakashima T,
Nakamura R, Tsuda T.
Neurological abnormalities in cognitively impaired but not demented elderly.
Acta Neurol Scand 2002;102:292-298.
Junichi Misumi, Megumi Nagano, Wenyuan Zhao, Kazuo Aoki.
Neurophysiological changes in rats subchronically treated with styrene
or its metabolites.
Journal of Occupational Health 2000;42:328-335.
Tongxing Xie, Junichi Misumi, Kazuo Aoki, Wenyuan Zhao, Shu-Ying Liu.
Absence of p53-mediated G1 arrest with induction of MDM2
in sterigmatocystin-treated cells.
Int J Oncol 2000;17:737-742.
Zhang X, Zhao W, Zhang Z, Wang J, Yan X, Xie T, Mi J, Bo Y,
Sun X, Misumi J, Aoki K.
Comparative study on drinking water between high and relatively
low risk areas of gastric cancer in Zanhuang county.
J Chin Public Health 1999;18:172-173.
Wenyuan Zhao, Kazuo Aoki, Tongxing Xie, Junichi Misumi.
Electrophysiological changes induced by different doses
of 1-bromopropane and 2-bromopropane.
J Occup Health 1999;41:1-7.
Zhang X, Sun X, Zhao W, Yan X, Wang J, Zhang Z, Mi J, Xie T, Wang H,
Misumi J, Aoki K.
Seroepidemiological study on Helicobacter pylori infection
in rural adult residents.
Chin J Epidemiol 1999;20:212-214.
Zhang X, Zhao W, Xia Y, Yan X, Wang J, Mi J, Zhang Z, Xie T,
Sun X, Cao W, Wang F, Misumi J, Aoki K.
Detection of serum pepsinogenⅠ, Ⅱ, gastrin and Helicobacter pylori antibody
in high and relatively low risk areas of gastric cancer in Zanhuang country.
Chin J Dig 1999;19:188-190.
Zhang X, Zhang Z, Zhao W, Wang J, Yan X, Xie T, Mi J, Bo Y, Sun X,
Cao W, Wang H, Bian L, Wang F, Misumi J, Aoki K.
Dietary and lifestyle questionnaire survey in the high and relatively
low area of gastric cancer in Zanhuang county.
J Chin Public Health 1998;17:246-248.
Takashi Kimura, Junichi Misumi, Toshio Goto, Wenyuan Zhao, Kazuo Aoki.
Electrophysiological and biochemical effects of exposure
to 2, 5-hexanedione on peripheral nerve in experimental diabetic rats.
J Occup Health 1998;40:148-153.
W Zhao, H Zhu, Z Yu, K Aoki, J Misumi, X Zhang.
Long-term effects of various iodine and fluorine doses
on the thyroid and fluorosis in mice.
Endoc Regul 1998;32:63-70.
Wenyuan Zhao, Junichi Misumi, Takato Yasui, Kazuo Aoki, Takashi Kimura.
Relationship between 2, 5-hexanedione concentrations in nerve, serum,
and urine alone or under co-treatment with different doses of methyl ethyl ketone,
acetone, and toluene.
Neurochem Res 1998;23:837-843.
Wenyuan Zhao, Junichi Misumi, Takato Yasui, Kazuo Aoki, Takashi Kimura.
Effects of methyl ethyl ketone, acetone, or toluene coadministration
on 2,5-hexanedione concentration in the sciatic nerve, serum,
and urine of rats.
Int Arch Occup Environ Health 1998;71:236-244.
Kazuo Aoki, Junichi Misumi, Takashi Kimura, Wenyuan Zhao, Tongxin Xie.
Evaluation of cutoff levels for screening of gastric cancer using serum
pepsinogens and distributions of levels of serum pepsinogen Ⅰ, Ⅱ and
of PG Ⅰ/ PG Ⅱ ratios in a gastric cancer case-control study.
J Epidemiol 1997;7:143-151.
Kazuo Aoki, Junichi Misumi.
Statistical Analysis of Serum PepsinogenⅠ(PGⅠ)and Ⅱ(PGⅡ) Levels,
PGⅠ/PGⅡ Ratios and Serum Gastrin Levels in a General Population.
Environmental Health and Preventive Medicine 1996;1:136-143.
Kazuo Aoki, Wenyuan Zhao, Junichi Misumi, Takato Yasui,
Masanobu Kudo.
Changes in 2, 5-Hexanedione Concentration in the Sciatic Nerve,
Serum and Urine of Rats Induced by Combined Administration
of 2,5-Hexanedione with Acetone or Methyl Ethyl Ketone.
Journal of Occupational Health 1996;38:30-35.
Takato Yasui, Wenyuan Zhao, Junichi Misumi, Kazuo Aoki,
Akira Shimaoka, Masanobu Kudo.
Influence of Different Doses of Methyl Ethyl Ketone
on 2,5-Hexanedione Concentrations in the Sciatic Nerve, Serum,
and Urine of Rats.
Journal of Occupational Health 1995;37:19-24.
Sekiguchi H, Tamaki Y, Kondo Y, Nakamura H, Hanashiro K, Yonemoto K, Moritani
T, Kukita I. 2018. Surface electromyographic evaluation of the neuromuscular activation of
the inspiratory muscles during progressively increased inspiratory flow under inspiratory-resistive
loading. Physiol Int. 105(1):86-99.
Ling, H., K. Hanashiro,T.H. Luong, L. Benavides, K. Fukasawa. 2015.
Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification.
Cell Cycle 14: 544-53. *L.H. and K.H. contributed equally to this work.
Tarapore, P. Hanashiro, K.,and Fukasawa, K. 2012. Analysis of centrosome
localization of BRCA1 and its activity in Suppressing Centrosomal aster formation.
Cell Cycle 11: 2931-2946.
Hanashiro, K.,Brancaccio, M., and Fukasawa, K. 2011. Activated ROCK II
by-passes the requirement of the CDK2 activity for centrosome duplication and amplification.
Oncogene 30: 2188-2197.
Hanashiro, K., M. Kanai, Y. Geng, P. Sicinski, and K. Fukasawa. 2008. Roles
of cyclins A and E in induction of centrosome amplification in p53-compromised cells. Oncogene
27: 5288-5302.
Venugopal, J.*, K. Hanashiro*, and Y. Nagamine. 2007. Regulation of PAI-1 gene
expression during adipogenesis. J Cell Biochem 101:369-380. *J.V. and K.H. contributed equally
to this work.
Shimada, S., M. Sunagawa, K. Hanashiro, M. Nakamura, and T. Kosugi. 2007. RNA interference
targeting embryonic myosin heavy chain isoform inhibited mRNA expressions of phenotype markers
in rabbit cultured vascular smooth muscle cells. Heart Vessels 22:41-47.
Ohta, S.*, K. Hanashiro*, M. Sunagawa, T. Tono, M. Suzuki, and T. Kosugi. 2007. Involvement of
Epstein-Barr virus (EBV)-encoded latent membrane protein (LMP)-1 in the potentiation of C epsilon
mRNA expression in human tonsil-derived cells. Eur Arch Otorhinolaryngol 264:245-250. *S.O. and K.H.
contributed equally to this work.
Kanai, M., K. Hanashiro, S. H. Kim, S. Hanai, A. H. Boulares, M. Miwa, and K. Fukasawa. 2007.
Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation. Nat Cell Biol
9:1175-1183.
Hanashiro, K., M. Sunagawa, T. Nakasone, M. Nakamura, and T. Kosugi. 2007. Inhibition of
IgE-mediated phosphorylation of FcepsilonRIgamma protein by antiallergic drugs in rat basophilic
leukemia (RBL-2H3) cells: a novel action of antiallergic drugs. Int immunopharmacol 7:994-1002.
Sunagawa, M., S. Shimada, K. Hanashiro, M. Nakamura, and T. Kosugi. 2006. Elevation of
intracellular cAMP up-regulated thrombomodulin mRNA in cultured vascular endothelial cells derived
from spontaneous type-II diabetes mellitus model rat. Endothelium 13:325-333.
Hanashiro, K., M. Sunagawa, Y. Tokeshi, T. Nakasone, S. Ohta, M. Nakamura, and T. Kosugi.
2006. Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE
secretion of rat IgE-producing hybridoma FE-3 cells. Eur J Pharmacol 547:174-183.
Hanashiro, K., S. Ohta, M. Sunagawa, M. Nakamura, M. Suzuki, and T. Kosugi. 2006. Modification of
Cepsilon mRNA expression by EBV-encoded latent membrane protein 1. Mediat Inflamm 2006:68069.
Venugopal, J.*, K. Hanashiro*, Z. Z. Yang, and Y. Nagamine. 2004. Identification and modulation of
a caveolae-dependent signal pathway that regulates plasminogen activator inhibitor-1 in insulin-resistant
adipocytes. Proc Natl Acad Sci USA 101:17120-17125. *J.V. and K.H. contributed equally to this work.
Nakamura, M., M. Sunagawa, K. Hanashiro, and T. Kosugi. 2004 (in Japanese). Bound thrombin is
noncompetitively inhibited by argathroban. Medicine and Biology 148:32-42.
Kinjoh, K., Nakamura, M., Sunagawa, M., Hanashiro, K., Kosugi, T. Exposure of threonyl residue
at position 10 in fibrinopeptide A is essential to the recognition by habutobin. Ryukyu Med J 2004;23:25-30.
Nakasone, T., K. Hanashiro, M. Nakamura, H. Sunakawa, and T. Kosugi. 2002. Mast cell-derived VEGF
enhances the passage of IgE FE-3 through the rat aortic endothelial cell monolayer. Int Arch Allergy Immunol
129:76-85.
Hanashiro, K., Y. Tokeshi, T. Nakasone, M. Sunagawa, M. Nakamura, and T. Kosugi. 2002. Azelastine and
suplatast shorten the distribution half-life of IgE in rats. Mediat Inflamm 11:61-64.
Tokeshi, Y., S. Shimada, K. Hanashiro, M. Sunagawa, M. Nakamura, and T. Kosugi. 2001.
The nucleotide sequence of dinitrophenyl-specific IgE and Fc(epsilon)RI alpha-subunit obtained from
FE-3 hybridoma cells. Hybrid Hybridomics 20:361-368.
Hanashiro, K., Y. Tokeshi, T. Nakasone, M. Sunagawa, M. Nakamura, and T. Kosugi. 2001. Analysis
of IgE turnover in non-sensitized and sensitized rats. Mediat Inflamm 10:217-221.
Hanashiro, K., M. Nakamura, T. Nakasone, Y. Tokeshi, and T. Kosugi. 2001. Tranexamic acid suppresses
the supernatant of mast cell-enhanced permeability of rat IgE across rat endothelial cells. . Inflamm Regen
21:659-664.
Hanashiro, K., M. Nakamura, T. Nakasone, Y. Tokeshi, and T. Kosugi. 2001. Permeability of rat IgE
across rat aortic endothelial cell is enhanced by histamine. Allergol Int 50:223-230.
Nakasone T, Hanashiro, K., Nakamura, M., Sunakawa, H., Kosugi, T. An improved method for the detection
of IgE FE-3 by ELISA using monoclonal anti-IgE FE-3 antibody. Ryukyu Med J 2001; 20:129-35.
Kinjoh, K., K. Hanashiro, Y. Tokeshi, and T. Kosugi. 2000 (in Japanese). Vascular endothelial growth
factor (VEGF) and tumor invasion/metastasis. Ryukyu Med. J. 19:193-201.
Nejime, T., K. Kinjoh, M. Nakamura, K. Hanashiro, M. Sunagawa, Y. Eguchi, and T. Kosugi. 2000. Habutobin
recognizes Thr(7) in the sequence of fibrinopeptide A of rabbit fibrinogen. Toxicon 38:1029-1041.
Tokeshi, Y., K. Hanashiro, I. Sugama, and T. Kosugi. 1998 (in Japanese). The effectiveness of perfusated
cell culture on the production of DNP-specific rat IgE from the FE-3 cells. Medicine and Biology 137:5-8.
Tokeshi, Y., M. Nakamura, K. Kinjoh, M. Sunagawa, K. Hanashiro, and T. Kosugi. 1998. Inhibition of habutobin
activities by habu antivenom. Toxicon 36:53-63.
Nakamura, M., K. Kinjoh, K. Hanashiro, M. Sunagawa, Y. Tokeshi, T. Ueda, and T. Kosugi. 1998. Inhibitory effect
of habu antivenom on fibrinopeptide A release induced by Trimeresurus flavoviridis crude venom. Toxicon 36:687-690.
Hanashiro, K., N. Tamaki, T. Kosugi, T. Kakazu, H. Kaneshima, and A. Saito. 1998 (in Japanese). The correlation between
the outbreaks of asthma attack and meteorologic parameters in Okinawa. Arerugi 47:434-448.
Kinjoh, K., T. Kosugi, M. Nakamura, K. Hanashiro, M. Sunagawa, Y. Tokeshi, and Y. Eguchi. 1997. Habutobin splits
the Arg16-Gly17 bond in the A alpha chain of rabbit fibrinogen. Thromb Haemost 77:1127-1128.
Kinjoh K, Nakamura M, Sunagawa M, Hanashiro K, Kosugi T: Concomitant measurement of fibrinopeptide
A and B in rabbit plasma using high-performance liquid chromatography. Jpn J Thromb Hemost 8 134-143, 1997.
Hanashiro, K., N. Tamaki, T. Koga, M. Nakamura, K. Kinjoh, and T. Kosugi. 1997. Inhibitory effect of azelastine
hydrochloride and suplatast tosilate on airway responses in sensitized rats following exposure to antigen. Int J Tissue React
19:163-169.
Hanashiro, K., T. Kosugi, M. Nakamura, and M. Sunagawa. 1997. Differences between changes of antigen-specific IgE
antibody level and those of IgG antibody level estimated by enzyme-linked immunosorbent assay (ELISA) in rats following
sensitization with DNP-Ascaris. Jpn J Inflamm :51-56.
Sunagawa, M., K. Hanashiro, M. Nakamura, and T. Kosugi. 1996. Habutobin releases plasminogen activator (U-PA) from bovine
pulmonary artery endothelial cells. Toxicon 34:691-699.
Hanashiro, K., M. Nakamura, N. Tamaki, and T. Kosugi. 1996. Production of a monoclonal dinitrophenyl-specific rat IgE and
establishment of an IgE capture ELISA for estimating the concentration of rat IgE antibodies to dinitrophenyl-Ascaris suum.
Int Arch Allergy Immunol 110:371-379.
Hanashiro, K., T. Kosugi, N. Tamaki, M. Sunagawa, and M. Nakamura. 1996. Identification of IgE with low molecular weight from
serum of rats sensitized with DNP-Ascaris. Ryukyu Med. J. 16:111-116.
Tamaki N, Kosugi T, Hanashiro K, Nakamura M: Physiological significance of protease in airway secretion
and the control of inflammation in airway tract by protease inhibitor. Ryukyu Med J 15 121-126, 1995.
Tamaki, N., K. Hanashiro, S. Saitoh, M. Nakamura, and T. Kosugi. 1995. Evaluation of airway responses by measurement of the
respiratory resistance in rats under nonanesthetized conditions. J. Jpn. Bronchoesophagol. Soc. 46:464-475.
Hanashiro, K., M. Sunagawa, S. Saitoh, M. Nakamura, and T. Kosugi. 1995. Administration of histamine-rat gammmaglobulin
conjugate suppresses IgE production in rats. Ryukyu Med. J. 15:13-17.
Sunagawa, M., K. Hanashiro, K. Kinjoh, Y. Masuda, M. Nakamura, and T. Kosugi. 1994 (in Japanese). Establishment of the method
for estimating the level of IgG1 in rats and its application. Medicine and Biology 129:129-132.
Saitoh, S., N. Tamaki, M. Nakamura, K. Hanashiro, and T. Kosugi. 1994 (in Japanese). Changes of soluble CD23 in patients with nasal
allergy treated by ketotifen. Otologia Fukuoka 40:440-445.
Hanashiro, K., N. Tamaki, M. Nakamura, and T. Kosugi. 1994 (in Japanese). Proposal of the new concepts of antiallergic drugs from the
results of animal experiments. Jpn. J. Inflamm. 14:499-507.
Nakamura, M., K. Hanashiro, and T. Kosugi. 1993. A modification of the ELISA-double sandwich method for estimating
the concentration of habutobin. Toxicon 31:1325-1328.
Kosugi, T., S. Saitoh, N. Tamaki, K. Hanashiro, K. Nakahodo, and M. Nakamura. 1993. Inhalation of platelet-activating
factor increases respiratory resistance in rats: determination by means of an astograph under nonanesthetized conditions.
Laryngoscope 103:428-430.
Kosugi, T., M. Nakamura, S. Saitoh, K. Kinjoh, and K. Hanashiro. 1992. Changes of rabbit platelet function following simultaneous
administration of Ticlopidine hydrochloride and Argipidine (MD-805). Int J Tissue React 14:141-148.
総 説
Hanashiro, K., Y. Tokeshi, S. Shimada, M. Sunagawa, M. Nakamura, and T. Kosugi.
(in Japanese). 2001. Interaction between IgE and its receptor (FcRI) in type-I allergy.
Ryukyu Med J 20:117-127.
Kosugi, T., M. Sunagawa, K. Hanashiro, K. Kinjoh, and M. Nakamura. (in Japanese).1997.
The role of proteolytic enzymes on ovulation-The role of fibrinolytic enzymes-. Ryukyu Med J 17:1-6.
Yonemaru, H., H. Karimata, H. Shimoji, K. Yamamoto, K. Hanashiro,* M. Fukami, G. Ouchi, Y. Tamaki, Y. Kondo, I. Kukita.
2015. Successful conservative management of a case of caustic esophagitis based on computed tomography assessment. Acute Med Surg doi:10. 1002/ams2. 149.
*Corresponding author.
Kazuhiko Hanashiro, Yoshikuni Nagamine. 2005. Screening method for agents useful
in treating diabetes. United States Patent Application Publication: US2005/0037956 A1.
等々力 英美
原 著
Willcox BJ, Willcox DC,Todoriki H, Fujiyoshi A, Yano K, Qimei He J, Curb JD, Suzuki M. Caloric Restriction, energy balance and healthy aging in Okinawans and Americans: Biomarker differences in septuagenarinas.The Okinawan J. American Studies. 2007;4:62-72.
Willcox BJ, Willcox DC, Todoriki H Fujiyoshi A, Yano K, Qimei He J, Curb JD, Suzuki M. Caloric Restriction, the Traditional Okinawan Diet, and Healthy Aging The Diet of the World’s Longest-Lived People and Its Potential Impact on Morbidity and Life Span. Ann. N.Y. Acad. Sci. 2007;1114:434-455.
Zheng KC, Todoriki H ,Katsumata Y, Gao WM, Keohavong P Analysis of p53 and K-Ras gene mutations in patients with chronic bronchitis using laser capture microdissection microscope and mutation detection. NingenDock 2007;21:19-21.
Harada K, Koizumi A, Saito N, Inoue K, Yoshinaga T, Date C, Fujii S, Hachiya N, Hirosawa I, Koda S, Kusaka Y, Murata K, Omae K, Shimbo S, Takenaka K, Takeshita T, Todoriki H, Wada Y, Watanabe T, Ikeda M. Historical and geographical aspects of the increasing perfluorooctanoate and perfluorooctane sulfonate contamination in human serum in Japan. Chemosphere. 2007;66:293-30.
等々力英美 沖縄の異文化接触による食変化と長寿性 老年歯科医学. 2007;21:19-21.
等々力英美 米国による戦後沖縄の保健医療政策 保健の科学 2007;21:373-378.
Okubo H, Sasaki S, Hirota N, Notsu A, Todoriki H, Miura A, Fukui M, Date C The influence of age and body mass index on relative accuracy of energy intake among Japanese adults. Public Health Nutr. 2006;9:651-657.
Willcox DC, Willcox BJ, Todoriki H, Curb JD, Suzuki M Caloric restriction and human longevity:What can we learn from the Okinawans Biogerontology 2006;7:173-177.
Tuekpe MKN, Todoriki H, Sasaki S, Zheng KC, Ariizumi M Potassium Excretion in Healthy Japanese Women was Increased by a Dietary Intervention Utilizing Home-Parcel Delivery of Okinawan Vegetables. Hypertens Res 2006;29:389-396.
Tuekpe MKN, Todoriki H, Zheng KC, Kouadio K, Ariizumi M Associations between lifestyle and mental health in a group of Japanese overseas workers and their spouses resident in Dusseldorf, Germany INDUSTRIAL HEALTH 2006;44(2):258-266.
Eslami B, Koizumi A, Ohta S, Inoue K, Aozasa O, Harada K, Yoshinaga T, Date C, Fujii S, Fujimine Y, Hachiya N, Hirosawa I, Koda S, Kusaka Y, Murata K, Nakatsuka H, Omae K, Saito N, Shimbo S, Takenaka K, Takeshita T, Todoriki H, Wada Y, Watanabe T, Ikeda M. Large-scale evaluation of the current level of polybrominated diphenyl ethers (PBDEs) in breast milk from 13 regions of Japan. CHEMOSPHERE 2005;63(4):554-561.
Koizumi A, Yoshinaga T, Harada K, Inoue K, Morikawa A, Muroi J, Inoue S, Eslami B, Fujii S, Fujimine Y, Hachiya N, Koda S, Kusaka Y, Murata K, Nakatsuka H, Omae K, Saito N, Shimbo S, Takenaka K, Takeshita T, Todoriki H , Wada Y, Watanabe T, Ikeda M Assessment of human exposure to polychlorinated biphenyls and polybrominated diphenyl ethers in Japan using archived samples from the early 1980s and mid-1990s ENVIRONMENTAL RESEARCH 2005;52(9):775-784.
Kouadio K, Zheng KC, Tuekpe MKN, Todoriki H, Ariizumi M Airway inflammatory and immunological events in a rat model exposed to toluene diisocyanate FOOD AND CHEMICAL TOXICOLOGY 2005;43(8):1281-1288.
Wada Y, Koizumi A, Yoshinaga T, Harada K, Inoue K, Morikawa A, Muroi J, Inoue S, Eslami B, Hirosawa I, Hirosawa A, Fujii S, Fujimine Y, Hachiya N, Koda S, Kusaka Y, Murata K, Nakatsuka H, Omae K, Saito N, Shimbo S, Takenaka K, Takeshita T, Todoriki H, Watanabe T, Ikeda M Title: Secular trends and geographical variations in the dietary intake of polybrominated diphenyl ethers (PBDEs) using archived samples from the early 1980s and mid 1990s in Japan. JOURNAL OF OCCUPATIONAL HEALTH 2005;47(3):236-241.
Todoriki H,Willcox DC.,Willcox BJ. The effects of post-war dietary change on longevity and health in Okinawa. Okinawan J.Amer Studies 2004;1:52-61.
Willcox B, Todoriki H, Willcox D, Suzuki M, Yano K, Abbott R, Rodriguez B, Curb J Early life caloric restriction and exceptional survival in Okinawa. A half century of population data. GERONTOLOGIST 2003;43:2.
Kabuto M, Yonemoto J, Sone H, Imai H, Todoriki H, Kaneko T, Yamamoto R, Yamaguchi T. Correlation between fish intake and dioxin in human milk at the individual level. Organohalogen Compd 2001;52:337-339.
Kui-Cheng Zheng, Dong-Xiao Nong, T. Morioka, H. Todoriki and M.Ariizumi ELEVATED INTERLEUKIN-4 AND INTERLEUKIN-6 IN RATS SENSITIZED WITH TOLIENE DIISOCYANATE Indutrial Health 2001;39:334-339.
Kui-Cheng Zheng, M.Ariizumi, H.Todorikiand Dong-Xiao Nong. CYTOKINE PROFILES IN AIRWAYS OF RATS EXPOSED TO TOLUENE DIISOCYANATE J. Occupational Health 2001;43:39-45.
Minoru Takakura, Seizo Sakihara, Akira Shiroma, Hidemi Todoriki, and Yoshiko Ozasa. RISK FACTORS FOR CIGARETTE SMOKING AMOUNG HIGH SCHOOL STUDENTS IN OKINAWA, JAPAN J. Epidemiol. 2000;10:140-148.
Willcox BJ, Suzuki M, Willcox DC, Todoriki H, Akisaka M, Hensrud PLASMA HOMOCYSTEINE LEVELS IN JAPANESE MEN AND WOMEN J. Invest.Med. 2000;48:141.
Willcox BJ, Hensrud DD, Suzuki M, Todoriki H, Akisaka M, HOMOCYSTEINE LEVELS IN ELDERLY JAPANESE J. Am. Geriatr. Soc. 1999;47:A37-37.
K.Zheng, A.A.Adjei, M.Shinjo, S. Shinjo, H. Todoriki and M. Ariizumi EFFECT OF DIETARY VITAMIN E SUPPLEMENTATION ON MURINE NASAL ALLERGY J. of Med. Sci. 1999;318:49-54.
H.Todoriki,M. Ariizumi,I.Ashitomi and M.Suzuki DESIGNING THE OKINAWA FOOD FREQUECY QUESTIONNARIE. J.Epidemiol. 1998;8:74.
Kui-Cheng Zheng,M.Ariizumi,H.Todoriki and M Shinjo CYTOKINE PRODUCTION BY SPLENOCYTES AND THYMOCYTES IN MICE AFTER INTRANASAL EXPOSURE TO TOLUENE DIISOCYANETE J.Occup. Health 1998;40:279-284.
K.Naka,D.Craig Willcox, H.Todoriki and T.Kageyama SUCIDE IN OKINAWA FROM AN INTERNATIONAL PERSPECTIVE:A CONSIDERATION OF SOCIO-CULTURAL FACTORS Ryukyu.Med.J. 1998;18:1-10.
Willcox BJ, Tariq N, Cunnane S, Fuchigami K, Willcox DC, Suzuki M, Todoriki H , Kinjo S, Komatsu H, Nakahara S, Mibu R, Iwamoto T, Ishikawa M, Shimizu H, Jenkins DJA SERUM FATTY ACID PROFILE AND PSA IN JAPANESE AND CANADIAN MEN FASEB J. 1996;10:3170.
H.Tsuchiya,K.Yamada,H.Todoriki and T.Hayashi URINARY EXCRETION OF TETRAHYDRO-BETA-CARBOLINES INFLUENCED BY FOOD AND BEVERAGE INGESTION IMPLIES THEIR EXOGENEOUS SUPPLY VIA DIETARY SOURCES J.Nutritional Biochem. 1996;7:237-242.
H.Tsuchiya,N.Takagi H.Todoriki and T.Hayashi METABOLISM OF 1-METHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE AND ITS IN VIVO HYDROXYLATION DEFICIENCY IN INFANTILE AUTISM Clinical Biochemist-Reviews 1995;14:202.
Hironori Tsuchiya, K.Yamada, S.Ohtani, N.Takagi, H.Todorikiand T.Hayashi DETERNINATION OF TETRAHYDRO-BETA-CARBOLINES IN RAT BRAIN BY GAS CHROMATOGRAPHY-NEGATIVE ION CHEMICALIONIZATION MASS SPECTROMETRY WITHOUT INTERFERENCE FROM ARTIFIFACTUAL FORMATION J.Neurosci.Meth 1995;62:37-41.
HironoriTsuchiya, Hidemi Todoriki and Tokishi Hayashi METABOLIC HYDROXYLATION OF 1-METHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE IN MAN Pharmacol.Biochem. Behav 1995;52:677-682.
Shoichiro Tsugane, Gerson S. Hamada, Jose Maria de Souza, Sabina L. Gotlieb,Yutaka Takashima, Hidemi Todoriki,Michinori Kabuto, Kanae Karita,Momoko Yamaguchi, Shaw Watanabe and Ruy Laurenti LIFESTYLE AND HEALTH RELATED FACTORS AMONG RANDOMLY SELECTED JAPANESE RESIDENTS IN THE CITY OF SAO PAULO, BRAZIL, AND THEIR COMPARISON WITH JAPANESE IN JAPAN J. Epidemiology 1994;4:37-46.
Hironori Tsuchiya, Hidemi Todoriki and Tokishi Hayashi URINARY EXCRETION OF THE ENANTIOMERS OF 1-METHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE UNEQUAL ABANDANCE IMPLIES ENZYMATIC METABOLISMS IN MAN Naunyn-Schmiedeberg'sArchives of Pharmacology 1994;350:104-108.
Hironori Tsuchiya,Shigeru Ohtani,Nobuhiko Takagi,Hidemi Todoriki,and Tokishi Hayashi QUANTITATION OF URINARY 1,2,3,4-TETRAHYDRO-BETA-CARBOLINE AND 1-METHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY J. Pharmaceutical Sciences 1994;83:415-418.
Shoichiro Tsugane, Fred Gey, Yoshimi Ichinowatari, Yoshimichi Miyajima, Teruo Ishibashi, Shosui Matsushima, Yoko Hirota,Tsuneo Inami, Momoko Yamaguchi, Kanae Karita,Michinori Kabuto, Yutaka Takashima, Hidemi Todoriki, Mitsuhiro Tsuda,Masayuki Akabane,Yasuhiro Furuichi, Gerson Hamada and Shaw Watanabe CROSS-SECTIONAL EPIDEMIOLOGIC STUDY FOR ASSESSING CANCER RISKS AT THE POPULATION LEVEL II. BASELINE DATA AND CORRELATION ANALYSIS J. Epidemiology 1992;2:83-89.
Shoichiro Tsugane, Fred Gey, Yoshimi Ichinowatari, Yoshimichi Miyajima, Teruo Ishibashi, Shosui Matsushima, Yoko Hirota,Tsuneo Inami, Momoko Yamaguchi, Kanae Karita,Michinori Kabuto, Yutaka Takashima, Hidemi Todoriki, Mitsuhiro Tsuda,Masayuki Akabane Yasuhiro Furuichi, Gerson Hamada and Shaw Watanabe CROSS-SECTIONAL EPIDEMIOLOGIC STUDY FOR ASSESSING CANCER RISKS AT THE POPULATION LEVEL I. STUDY DESIGN AND PARTICIPATION RATE J. Epidemiology 1992;2:75-81.
D.Dominicus, Hidemi Todoriki, Takashi Akamatsu and Makoto Ariizumi EFFECT OF ALCOHOL ON BLOOD LEVELS OF BRANCHED CHAIN α-KETO ACIDS IN MALE WISTAR RATS Alcohol and alcoholism 1991;26:597-603.
Tokishi Hayashi, Hidemi Todoriki and Yoshio Iida DETERMINATION OF 1,2,3,4-TETRAHYDRO-BETA-CARBOLINE AND 1-METHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE IN HUMAN URINE BY CAPILLARY GC/NICIMS Mass Spectrometry 1991;39:35-40.
軍神宏美, 等々力英美,今村経明, 加藤範久,赤松隆,野口忠, 内藤博 ラットにおける臓器中微量元素濃度―Cr、Co,Ni,Mo,Mn,Cu,Zn,Fe―に及ぼす食餌Ca量の影響 Biomed Res Trace Elem 1990;1:113-114.
Tokishi Hayashi, Hidemi Todoriki and Yoshio Iida HIGHLY SENSITIVE METHOD FOR THE DETERMINATION OF 1-METHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE USING COMBINED CAPILLARY GAS CHROMATOGRAPHY/NEGATIVE ION CHEMICAL IONIZATION MASS SPECTROMETRY J. Chromatogr. Biomed. Appl. 1990;528:1-8.
Hidemi Todoriki, Tokishi Hayashi, Hiromi Gunshin, D.Dominicus, Tatsuya Todoriki and Takashi Akamatsu DETERMINATION OF HIPPURIC ACID IN URINE BY GC/MS -IN VIVO METABOLISM OF TOLUENE TO HIPPURIC ACID ON TOLUENE POISONING- Mass Spectrometry 1990;38:1-8.
D.Dominicus, Hidemi Todoriki, Takashi Akamatsu and Hiromi Gunshin PRESENT HEALTH SITUATION IN TANZANIA Japanese . of Public Health 1990;J37:118-125.
Takashi Akamatsu, Hidemi Todoriki, Masako Kusumoto and Tokishi Hayashi STUDIES ON TOLUENE/ HIPPURIC ACID METABOLISM ON CHRONIC EXPOSURE OF TOLUENE:GC/MS DETERMINATI -ON USING STABLE ISOTOPIC METHOD Environmental and Occupational Chemical Hazards 1988;8:443-446.
Hidemi Todoriki, Keietsu Tamagake, Masamichi Tsuboi and Takashi Akamatsu ESTIMATION OF LINE WIDTH BY SELF- ABSORPTION MEASUREMENT USING FOURIER TRANSFORM INFRARED SPECTROSCOPY J. Spectrosc. Soc.Japan 1987;36(1):20-25.
鎌田 紘八、等々力英美、楠本 昌子、大石 幸子 毒性評価のためのマウス受精卵の In vitro 培養（４）－非発癌性変異原の受精卵の発育におよぼす影響－ 日薬理誌 1986;88:167-172.
Hidemi Todoriki, Tokishi Hayashi and Hiroshi Naruse HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR THE SCREENING DISORDERS OF THE AROMATIC ACID METABOLISM USING A MULTI-DETECTION SYSTEM J. Chromatogr., 1984;310:273-281.
Hidemi Todorikiand Akiko Y. Hirakawa A NEW EXCITING METHOD IN LASER FLUOROMETRY AND RAMAN SPECTROSCOPY USING AN OPTICAL FIBER - AN APPLICATION TO HIGH PERFORMANCE LIQUID CHROMATOGRAPHY ? Chem. Pharm. Bull 1984;32:193-197.
Hidemi Todoriki, Tokishi Hayashi, Hiroshi Naruse and Akiko Y. Hirakawa SENSITIVE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF CATECHOLAMINES IN RAT BRAIN USING A LASER FLUOROMETRIC DETECTION SYSTEM J.Chromatogr. 1983;276:45-54.
Hidemi Todoriki, Tokishi Hayashi,Hiroshi Naruse and Seiji Ikeda PREPURIFICATION AND DERIVATIZATION OF ALPHA -KETO ACIDS USING HYDRAZIDE GEL -APPLICATION IN GC AND GC/MS - J. Chromatogr 1982;232:394-399.
Tokishi Hayashi, Hironori Tsuchiya, Hidemi Todoriki and Hiroshi Naruse HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ALPHA-KETO ACIDS IN HUMAN URINE AND PLASMA Anal. Biochem. 1982;122:173-179.
Tokishi Hayashi, Hidemi Todorikiand Hiroshi Naruse HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ALPHA-KETO ACIDS J. Chromatogr 1981;224:197-204.
Hidemi Todoriki, Yoshifumi Nishimura,Shigesada Higuchi,Akiko Y. Hirakawa and Masamichi Tsuboi A SPECTROSCOPIC STUDY OF HYDROGEN-BONDS INVOLVING THE 2- THIOURACIL RESIDUE Bull. Chem. Soc.Japan 1980;53:1881-1887.
Hidemi Todoriki and Akiko Y. Hirakawa CW LASER FULUOROMETRY USING AN OPTICAL FIBER- AN APPLICATION TO HIGH PERFORMANCE LIQUID CHROMATOGRAPHY - Chem. Pharm. Bull 1980;28(4):1337-1339.
Kui-Cheng Zheng, Makoto Ariizumi.
Modulations of Immune Functions and Oxidative Status Induced
by Noise Stress. Journal of Occupational Health 2007;49:32-38.
Kui-Cheng Zheng, Hidemi Todoriki, Yuriko Katsumata,
Wei-Min Gao, Phouthone Keohavong.
Analysis of p53 and K-ras mutations in patients with chronic bronchitis
using laser capture microdissection microscope and mutation detection.
Ningen Dock 2007;21:66-68.
Kui-Cheng Zheng, J. C. Yalowich, V. E. Kagan and P. Keohavong.
Increased mutant frequencies in the HPRT gene locus of leukemia HL-60 cells
treated with succinyl acetone.
Cell Biology and Toxicology 2006;22:361-370.
Mallet KN Tuekpe, Hidemi Todoriki, Kui-Cheng Zheng,
Kouadio Kouame, Makoto Ariizumi.
Association between lifestyle and mental health in a group
of Japanese overseas workers and their spouses resident in Dusseldorf, Germany.
Industrial Health 2006;44:258-266.
Mallet KN Tuekpe, Hidemi Todoriki, Kui-Cheng Zheng,
Satoshi Sasaki, Makoto Ariizumi.
A significant increase in potassium excretion of healthy free-living women
in a delivery intervention study utilizing typical Okinawan vegetables.
Hypertension Research 2006;29:389-396.
Kouame Kouadio, Kui-Cheng Zheng, Mallet KN Tuekpe,
Hidemi Todoriki, Makoto Ariizumi.
Airway inflammatory and immunological events in a rat model exposed
to toluene diisocyanate.
Food and Chemical Toxciology 2005;43:1281-1288.
Phouthone Keohavong, Qing Lan, Wei-Min Gao, Kui-Cheng Zheng,
Hussam H Mady, Mona F Melhem and Judy L Mumford.
Detection of p53 and K-ras mutations in sputum of individuals exposed
to smoky coal emissions in Xuan Wei County, China.
Carcinogenesis 2005;26:303-308.
Kui-Cheng Zheng.
A preliminary study on the effect of myeloperoxidase
on etoposide-induced HPRT mutants in HL-60 cells.
Ryukyus Medical Journal 2004;23:85-91.
Kouame Kouadio, Kui-Cheng Zheng, Mallet KN Tuekpe and Makoto Ariizumi.
Effects of exposure to toluene diisocyanate on immunological functions
in a murine airway hypersensitivity model.
Ryukyus Medical Journal 2004;23:123-131.
Phouthone Keohavong, Wei-Min Gao, Kui-Cheng Zheng, Hussam Mady,
Qing Lan, Mona Melhem, and Judy Mumford.
Detection of K-ras and p53 mutations in sputum samples of lung cancer patients
using laser capture microdissection microscope and mutation analysis.
Analytical Biochemistry 2004;324:92-99.
Kui-Cheng ZHENG, Kouame KOUADIO, Mallet K-N TUEKPE, Makoto ARIIZUMI.
Eosinophil Infiltration in Airways of Mice Exposed to Toluene Diisocyanate.
Journal of Occupational Health 2004;46:299-302.
Hiromi Yamamoto, Kui-Cheng Zheng and Makoto Ariizumi.
Influence of Heat Exposure on Serum Lipid and Lipoprotein Cholesterol
in Young Male Subjects.
Industrial Health 2003;41:1-7.
Kui-Cheng Zheng and Makoto Ariizumi.
Interleukin-4 and Interleukin-5 Expression in Mice Exposed
to 2, 4-Toluene Diisocyanate.
Journal of Occupational Health 2002;44:421-426.
Hiromi Yamamoto, Kui-Cheng Zheng, and Makoto Ariizumi.
A Study of the Hand-Arm Vibration Syndrome in Okinawa,
a Subtropical Area of Japan.
Industrial Health 2002;40:59-62.
Hiromi Yamamoto, Kui-Cheng Zheng, and Makoto Ariizumi.
Changes of serum lipid in young male subjects exposed to thermal environment.
San Ei Shi 2002;44:12-14.
Kui-Cheng Zheng, Dong-Xiao Nong, Takamitsu Morioka,
Hidemi Todoriki and Makoto Ariizumi.
Elevated Interleukin-4 and Interleukin-6 in Rats Sensitized
with Toluene Diisocyanate.
Industrial Health 2001;39:334-339.
Kui-Cheng Zheng, Makoto Ariizumi, Hidemi Todoriki and Dong-Xiao Nong.
Cytokine Profiles in Airways of Rats Exposed to Toluene Diisocyanate.
Journal of Occupation Health 2001;43:39-45.
Kui-Cheng Zheng, Andrew A Adjei, Masaki Shinjo, Sumie Shinjo,
Hidemi Todoriki, Makoto Ariizumi.
Effect of Dietary Vitamin E Supplementation on Murine Nasal Allergy.
The American Journal of Medical Sciences 1999;318:49-54.
Kui-Cheng Zheng, Makoto Ariizumi, Hidemi Todoriki and Masaki Shinjo.
Cytokine Production by Splenocytes and Thymocytes in Mice
after Intranasal Exposure to Toluene Diisocyanate.
Journal of Occupational Health 1998;40:279-284.
Kun Fan Fong, Kui Cheng Zheng, Hidemi Todoriki and Makoto Ariizumi.
Studies on the effect of noise stress on immune response of mice.
Ryukyu Medical Journal 1997;17:189-197.
Kun Fan Fong, Kui Cheng Zheng, Hidemi Todoriki and Makoto Ariizumi.
Studies on the effect of noise stress on immune response of rats.
Ryukyu. Medical Journal 1997;17:95-100.
Kui-Cheng Zheng, Jian-Ming Yu, Wen-Ming Xu, Jia-Xian He.
Prevalence of poliomyelitis in Fujian Province from 1955 to 1993.
Fujian Journal of Preventive Medicine 1993;2.
勝亦 百合子 1999～2007年
原 著
Arai A, Ishida K, Tomimori M, Katsumata Y, Grove JS, Tamashiro H.
Association between lifestyle activity and depressed mood among home-dwelling
older people: A community-based study in Japan.
Aging & Mental Health 2007,11:547-555.
Katsumata Y, Arai A, Tamashiro H.
Contribution of falling and being homebound statuses
to subsequence functional changes among the Japanese elderly living
in a community.
Archives of Gerontology and Geriatrics 2007;45:9-18.
Katsumata Y, Arai A, Tamashiro H.
Nonlinear Association of Higher-Level Functional Capacity
with the Incidence of Falls in Japan.
American Journal of Physical Medicine and Rehabilitation 2006;85:688-693.
Katsumata Y, Arai A, Ishida K, Tomimori M, Denda K, Tamashiro H.
Gender differences in the contributions of the risk factors
to depressive symptoms among the elderly persons dwelling in a community, Japan.
International Journal of Geriatric Psychiatry 2005;20:1084-1089.
Arai A, Katsumata Y, Konno K, Tamashiro H.
Sociodemographic Factors associated with Incidence of Dementia
in Senior Citizens of a Small Town in Japan.
Care Management Journals 2004;5:159-165.
Konno K, Katsumata Y, Arai A, Tamashiro H. Functional status
and active life expectancy among senior citizens in a small town in Japan.
Archives of Gerontology and Geriatrics 2004;38:153-166.
Kagohashi T, Takarada T, Hasegawa H, Katsumata Y, Kuga M,
Okamoto H, Kaneko H, Ishihara Y.
Electrical resistivity and thermoelectric power of a quasi-one-dimensional
Nb3Te4 single crystal inserted with mercury: HgxNb3Te4.
Journal of Physics: Condensed Matter 1999;11:6373-6384.
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